{"id":19252,"date":"2025-04-08T15:07:24","date_gmt":"2025-04-08T12:07:24","guid":{"rendered":"https:\/\/reganews.co.il\/en\/?p=19252"},"modified":"2025-04-08T15:09:01","modified_gmt":"2025-04-08T12:09:01","slug":"the-howl-returns-as-dire-wolves-walk-again","status":"publish","type":"post","link":"https:\/\/reganews.co.il\/en\/the-howl-returns-as-dire-wolves-walk-again\/","title":{"rendered":"The Howl Returns as Dire Wolves Walk Again"},"content":{"rendered":"<p>A groundbreaking scientific achievement was revealed Monday in a TIME Magazine cover story. The American biotechnology company <em>Colossal Biosciences<\/em> has successfully brought the dire wolf back to life\u2014a prehistoric apex predator that went extinct nearly 10,000 years ago. Three pups, named Romulus, Remus, and Khaleesi, were born in recent months at a secret wildlife preserve in the United States, after the company performed precise genetic editing on gray wolf DNA to match the reconstructed genome of the ancient predator.<\/p>\n<p><strong>Reconstructing the Genetic Code Using Ancient Bone Samples<br \/>\n<\/strong>Scientists managed to recreate the genetic blueprint of the extinct species using ancient bone samples. To align the gray wolf\u2019s DNA with that of the dire wolf, researchers made 20 targeted modifications across 14 genes. These changes produced larger animals with powerful jaws, white fur, and a wilder, more primitive demeanor. The pups bear a closer resemblance to their ancient ancestor than to any modern domestic dog. The animals were birthed via surrogacy, and the company emphasized that none of the surrogate mothers suffered as a result of the process.<\/p>\n<p><strong>Not Just a Symbolic Breakthrough, But a Revolutionary Technology<br \/>\n<\/strong>This development is not merely symbolic\u2014it represents a technological revolution. The technique could help conserve species that are extinct or on the brink, such as the red wolf, the dodo, the Tasmanian tiger, and the woolly mammoth. The company reported that it has already successfully cloned four red wolves, with the goal of expanding their genetic diversity and preventing their complete extinction.<\/p>\n<blockquote class=\"twitter-tweet\">\n<p dir=\"ltr\" lang=\"en\">Meet the first dire wolves to exist in over 10,000 years <a href=\"https:\/\/t.co\/PiXmBEGrk6\">https:\/\/t.co\/PiXmBEGrk6<\/a> <a href=\"https:\/\/t.co\/NJl20cxp80\">pic.twitter.com\/NJl20cxp80<\/a><\/p>\n<p>\u2014 TIME (@TIME) <a href=\"https:\/\/twitter.com\/TIME\/status\/1909328283100996094?ref_src=twsrc%5Etfw\">April 7, 2025<\/a><\/p><\/blockquote>\n<p><script async src=\"https:\/\/platform.twitter.com\/widgets.js\" charset=\"utf-8\"><\/script><\/p>\n<p><strong>&#8220;For Us, This Is Just the Beginning&#8221;<br \/>\n<\/strong>Not all scientists, however, are celebrating. Some warn of unpredictable environmental consequences and raise ethical and biological concerns about reintroducing extinct species into the modern world. \u201cThis might be a moral attempt to right a human wrong\u2014or it could be a dangerous act of playing with fire,\u201d critics noted.<\/p>\n<figure id=\"attachment_19255\" aria-describedby=\"caption-attachment-19255\" style=\"width: 800px\" class=\"wp-caption alignnone\"><img fetchpriority=\"high\" decoding=\"async\" class=\"wp-image-19255 size-large\" src=\"https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2-1024x683.jpg\" alt=\"\" width=\"800\" height=\"534\" srcset=\"https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2-1024x683.jpg 1024w, https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2-300x200.jpg 300w, https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2-768x512.jpg 768w, https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2-1536x1024.jpg 1536w, https:\/\/reganews.co.il\/en\/wp-content\/uploads\/2025\/04\/woofwoof2.jpg 2048w\" sizes=\"(max-width: 800px) 100vw, 800px\" \/><figcaption id=\"caption-attachment-19255\" class=\"wp-caption-text\">&#8220;A dangerous act of playing with fire.&#8221; Skeleton of a dire wolf on display at a museum | Photo credit: Shutterstock<\/figcaption><\/figure>\n<p>The young wolves currently live in a 2,000-acre enclosed area, and are already howling in ancient tones not heard since the Ice Age. \u201cFor us, this is just the beginning,\u201d said the company. \u201cIf we can preserve life that was lost, we can also save the life that\u2019s disappearing right now.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Colossal Biosciences has brought the extinct dire wolf back to life, calling it \u201cjust the beginning.\u201d<\/p>\n","protected":false},"author":8,"featured_media":19254,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1,80,2277,65],"tags":[3976,3972,3973,3974,3969,3970,3971,3975],"class_list":["post-19252","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-culture","category-environment","category-history","category-world","tag-biotech-innovation","tag-cloning","tag-colossal-biosciences","tag-de-extinction","tag-dire-wolf","tag-extinction","tag-prehistoric-species","tag-red-wolf"],"yoast_head":"<!-- This site is optimized with the Yoast SEO Premium plugin v22.7 (Yoast SEO v24.7) - 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